Issue130

Title Default Masses in pConfig are WRONG
Priority urgent Status finished
Superseder Nosy List gtheophall, pzmao
Assigned To pzmao Keywords

Created on 2023-04-08.23:36:19 by gtheophall, last changed by pzmao.

Messages
msg350 (view) Author: pzmao Date: 2023-04-20.09:25:10
Hello,

I am very sorry to notice your question on the forum so late.

I think pLink's pConfig default BS3 crosslinker mass are right. Maybe your 
calculations are wrong.

BS3 linker after reaction has 10 hydrogen atoms, and the added mass is 138. 
Monolink by H2O has 12 hydrogen atoms, and the added mass is 156. As you said, 
monolink will probably lose an H, adding a mass of 155 also exists. There is a 
lot of literature(https://doi.org/10.1016/j.ijms.2019.116184) and the Thermo 
product documentation(https://assets.fishersci.com/TFS-
Assets/LSG/manuals/MAN0011542_BS3_d0d4_BS2G_d0d3_UG.pdf) that support these mass 
values.

BS3_heavy is replacing four hydrogen atoms with four deuterium atoms, which is 
2H.

Regards,
Pengzhi Mao
History
Date User Action Args
2023-05-24 16:22:14pzmaosetstatus: processing -> finished
2023-04-20 09:25:12pzmaosetstatus: chatting -> processing
assignedto: pzmao
messages: + msg350
nosy: + pzmao
2023-04-09 00:30:31gtheophallsetfiles: - PLINK Error.png
2023-04-09 00:30:25gtheophallsetmessages: - msg348
status: unread -> chatting
2023-04-08 23:36:21gtheophallcreate