Hi irleader,

`param.txt` is for `pnovo3_search.exe`, but it will be rewritten everytime you 
click on `Search` on GUI.

Here is a way. You can change the file `pNovo-template/param.txt` in the 
installation directory, which is the template for `pnovo3_search.exe`. Remember 
to backup before you change the file.

Not sure if it satisfies your demands because I also have not tried this before. 
Contact me if you meet questions.

jinyangl